Peste des petits ruminants

Up close: exterior

Like all of the viruses in the Paramyxoviridae family, PPRV is an enveloped virus.

PPRV ultrastructure (click on the image to enlarge it)

In this virus,

  • The viral enveloppe is formed by a double layered lipid membrane 5 nanometres thick borrowed from the infected cell when the virion is formed.

  • The outside of the envelope is spiked with two kinds of spicules, each 10 nanometres long, which are inserted into the membrane.

    These spicules are two glycoproteins, the fusion (F) protein and hemagglutinin H.

  • The inside surface of the envelope is lined with the matrix (M) protein.

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